Plinest – Dr Audrey & Dr R Clinic


What is


PLINEST® and NEWEST® contains PN-HPT™, the ORIGINAL PN from Italy, with more than 100 published clinical studies .

PN-HPT™ (Polynucleotide – Highly Purified Technology) is a DNA fragment extracted from Italian Trout Fish using HPT™ technology developed and patented by Mastelli Aesthetic, Italy.

With 70 years’ worth of research, Mastelli Aesthetic perfected HPT™ technology to assures only the highest purification levels of PN are extracted, resulting in superior efficacy and safety in compliance even with the highest pharmaceutical standards.

The entire manufacturing process from the selection of the best fish to the finished product is closely monitored and controlled by Mastelli Aesthetic in Italy.

Not all PN are the same, only PN developed by Mastelli Aesthetic certified as PN-HPT™.


from ITALY


of Research


Published Clinical

How PLINEST Works?

PLINEST is clinically proven to improve OVERALL SKIN HEALTH from WITHIN by:

Promoting bio-revitalisation to reverse signs of ageing

Regenerating fibroblast and collagen to repair damaged skin

Improving hydration and elasticity

Improve overall skin health for a smooth, flawless and radiance skin.


  • Promote bio-revitalisation to reverse signs of ageing
  • Regenerate fibroblast and collagen to repair damaged skin
  • Improve hydration and elasticity
  • Restore glowing skin radiance and youthfulness

Before & After


Face, Neck, Scalp, hands, body and private parts

Typically around 45 minutes including the application of numbing cream and for its effect to set in


One of the advantages of the Plinest treatment is the minimal downtime. Patients can usually return to their regular activities immediately after the procedure. However, slight redness, swelling, bruising or itching at the injection site is normal and typically resolves within a few days. Applying a cool pack to the affected area can help alleviate these symptoms

2-3 sessions recommended for results lasting up to 1 year